Testosterone and Erectile Dysfunction (ED)
Hormonal imbalance especially in production and secretion of sex hormones may be the root cause of the erectile dysfunction (ED) you experience. Testosterone is the main hormone in men, which drives the sexual drive and function. Such hormonal imbalances will affect your capability to maintain a healthy sex life by decreasing your blood testosterone levels. Hormone levels decrease as men age. Usually, the hormones lost are not replaced.
You have to note that men also produce estrogen in their fat tissues, which is a female sex hormone. A proportional increase in body fat composition of men with obesity problem triggers increased generation of estrogen, which acts against testosterone and decreases its production through hormonal feedback mechanisms. Both alcohol abuse and unhealthy eating are estrogenic by exacerbating obesity and reducing the metabolic degradation of estrogen in the liver through their toxic effects. Diabetes may also add to the problem, and complicate hormonal disturbances in your body.
Adequate blood testosterone concentrations are paramount for the regulation of phosphodiesterase-5 production for its actions exerted by controlling healthy vascular responses in penile tissue. An age related decline of blood testosterone levels is reported in approximately 20 to 30% of men, whereas testosterone deficiency is reported in up to 50% of men with metabolic syndrome or diabetes. Not surprisingly, men with ED inadequately responding to phosphodiesterase-5 inhibitors (PDE5Is) have been shown to benefit from hormonal replacement therapy with testosterone supplements.
However, testosterone replacement would increase the risk of having or exacerbating prostate cancer or benign prostate hyperplasia while improving ED problem. Prostate cancer patients treated with anti-testosterone hormonal medications represent the best examples of the ED due to lack of testosterone.